Remifentanil Patient-Controlled Analgesia for Labour: A Complete Audit Cycle

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Patient-controlled analgesia for labour using remifentanil: a feasibility study.

We have investigated the efficacy and safety of remifentanil in a patient-controlled analgesia device for labour in 21 women. Remifentanil was available in increasing doses (bolus doses 0.25-1.0 microg x kg(-1)) with and without a background infusion (0.025-0.05 microg x kg(-1) x min(-1)). A lockout time of 2 min was used. Thirteen out of 21 (62%) women chose to continue using remifentanil up t...

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Remifentanil patient controlled analgesia versus epidural analgesia in labour. A multicentre randomized controlled trial

BACKGROUND Pain relief during labour is a topic of major interest in the Netherlands. Epidural analgesia is considered to be the most effective method of pain relief and recommended as first choice. However its uptake by pregnant women is limited compared to other western countries, partly as a result of non-availability due to logistic problems. Remifentanil, a synthetic opioid, is very suitab...

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Patient controlled analgesia with remifentanil versus epidural analgesia in labour: randomised multicentre equivalence trial

OBJECTIVE To determine women's satisfaction with pain relief using patient controlled analgesia with remifentanil compared with epidural analgesia during labour. DESIGN Multicentre randomised controlled equivalence trial. SETTING 15 hospitals in the Netherlands. PARTICIPANTS Women with an intermediate to high obstetric risk with an intention to deliver vaginally. To exclude a clinically r...

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Remifentanil by patient-controlled analgesia compared with intramuscular meperidine for pain relief in labour.

BACKGROUND The pharmacokinetics of remifentanil suggests that it may be suitable for analgesia during labour. METHODS In an open pilot study, 36 women requesting meperidine for analgesia were recruited early in labour and randomized to receive either meperidine i.m. or remifentanil given as patient-controlled analgesia (PCA). Pain severity, sedation and anxiety were assessed with visual analo...

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Obstetric analgesia: a comparison of patient-controlled meperidine, remifentanil, and fentanyl in labour.

BACKGROUND To compare the analgesic efficacy of remifentanil with meperidine and fentanyl in a patient-controlled setting (patient-controlled analgesia, PCA). METHODS Parturients (n=159) were randomly assigned to receive remifentanil (n=52), meperidine (n=53), or fentanyl (n=54). Pain scores and an observer sedation scores were assessed hourly. Fetal outcome was evaluated with Apgar score, co...

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ژورنال

عنوان ژورنال: Anaesthesia and Intensive Care

سال: 2011

ISSN: 0310-057X,1448-0271

DOI: 10.1177/0310057x1103900421